SenatorBernie Sandersof Vermont dropped out of the Democratic presidential race on Wednesday, concluding a quest for the White House that began five years ago in relative obscurity but ultimately elevated him as a champion of the working class, a standard-bearer of American liberalism and the leader of a self-styled political revolution.

Mr. Sanders’s exit from the race establishes former Vice PresidentJoseph R. Biden Jr.as the presumptive nominee to challenge President Trump, and leaves the progressive movement without a prominent voice in the 2020 race.

In a live stream on Wednesday morning, Mr. Sanders, eloquent but without his characteristic spark, was by turns gracious and resolute as he announced his decision. “I cannot in good conscience continue to mount a campaign that cannot win and which would interfere with the important work required of all of us in this difficult hour,” Mr. Sanders said.

Though he made it clear that he viewed Mr. Biden as the party’s 2020 nominee, he said he would remain on the ballot in states that still have primaries and would continue to gather delegates – a move that would give him leverage to influence the Democratic platform and continue carrying his message.

“While this campaign is coming to an end, our movement is not,” he added.

In a race reshaped, and eclipsed, by the escalating coronavirus crisis, Mr. Sanders faced no realistic path to the nomination after a series of lopsided losses to Mr. Biden, beginning inSouth Carolinain late February and culminating with a string of losses last month in crucial states likeMichiganandFlorida.

With the public health emergency preventing both candidates from holding in-person campaign events, Mr. Sanders spent the last several weeks on the sidelines, delivering addresses via live stream and making occasional television appearances, while facingcalls from fellow Democrats to exit the raceand help unify the party behind Mr. Biden. Though Mr. Biden had been careful not to pressure Mr. Sanders, he had begun to move ahead as if the race were over, taking steps, for example, to beginhis search for a running mate.

•Text (excluding headline): The New York Times.