British lawmakers have soundly rejected Theresa May's Brexit deal, in the biggest defeat for any UK government in the modern parliamentary era.

After 200 speeches across eight days of debate, members of the House of Commons ignored the Prime Minister's final pleas and threw out the deal by 432 votes to 202.

The 230-vote margin of defeat -- more than the previous record of 166 in 1924 -- means the Prime Minister now faces a deep political crisis, with no clear path out of the mess.

Acknowledging the scale of the defeat, May said her government would give time for MPs to debate a motion of no-confidence.

Speaking moments after May's humiliating loss, opposition Labour leader Jeremy Corbyn called the defeat "catastrophic" and confirmed he would trigger a no-confidence vote. It would allow the House of Commons to "give its verdict on the sheer incompetence of this government," he said.

May now has 24 hours to save her government. If she loses the vote, it makes a general election more likely.

"The government has heard what the House has said tonight, but I ask members on all sides of the house to listen to the British people, who want this issue settled, and to work with the government to do just that," May told lawmakers.

Notwithstading the confidence vote, the Prime Minister now has three days to set out Plan B. In the coming days, she's expected to meet European leaders in Brussels to seek further concessions. During her speech after the vote, May also offered cross-party talks with lawmakers as an attempt to try and figure out a way forward.

"Every day that passes without this issue being resolved means more uncertainty, more bitterness and more rancor," May said. (CNN)